PRACTICAL ORGANIC CHEMISTRY Pour into 100 c.c. water, and extract with ether. Distil off the ether and crystallise the solid residue from petroleum spirit. Yield, 8 grams ; m. p. 58-60°. C()H;VCO.CH, + NH,OH.HCl-f- NaOH - C0H,C(NOH).CH, + NaCl + 3HaO. 2. Acetophenonesemicarbazone.—Mix i gram of semi- carbazide hydrochloride with I '5 grams of crystallised sodium acetate, and dissolve in the smallest quantity of warm water. Add i gram of acetophenone and sufficient spirit to produce a clear solution when hot. Continue to heat for a few minutes. On cooling, the semicarbazone deposits as a yellow, crystalline mass. CCH.VCO.CH., + NH,.NH.CO.NH.,HC1 + NaC,H,O2 = C(.H5C(N.NH.CONH,)CH,"'+ NaCl + C2H4Oo. Theoretical yield ; m. p. 185—• 188'. 3. Beckmann's Reaction.—Dissolve i gram of aceto- phenoneoxime in 30 c.c. anhydrous ether, and add gradually i'5 grams of powdered phosphorus pentachloride. Distil off the ether, and add a little water to the residue. On cooling, crystals of acetanilide separate. Recrystallise from water, and determine the melting point. 1. CGH5.C1NOH).CH3 + PCI, = C0H6.C(NC1).CH3 + POO, + HCL 2. CGH&C(NC1)CH3+ H,0 = C0HflNH.CO.CH3 + HCL 4. Benzoylacetone (Claiseris Reaction).—Six grams of dry, ! powdered sodium ethoxide are added to 20 grams of dry ethyl i acetate, and cooled in water. The sodium ethoxide is prepared by dissolving 4 grams of sodium in 40 c.c. absolute alcohol, and. ^ distilling off the excess of alcohol, first from the water-bath, and ' then from the metal-bath, in a current of dry hydrogen, the temperature of the bath being raised gradually to 200°, until ' ' nothing more passes over. The white cake is detached rapidly \ powdered, and the requisite quantity quickly weighed out and 1 added to the'ethyl acetate. After standing a quarter of an j hour, 10 grams of acetophenone are added, when sodium benzoyl | acetone begins to separate. A little ether is added, and, after 1 standing for a few hours, the sodium compound is filtered and ! washed with ether. The sodium compound is then dried in f trje air, dissolved in cold water, and acidified with acetic acid. p Benzoylacetoneseparates out. Yield,9—10grams; m.p.60—61°.